The goal of the text is to provide the practicing transfusion medicine professional with a review of the science and management of routine blood banking. This text is recommended for the reading of all blood bank personnel.
The current edition includes a new chapter on antibody screening, a review of the ABO, Rh and Kell antigens with a focus on the routine ABO/RhD typing methods, followed by a review of the antibody-specificities of donor red cells and cells from autoimmune patients. It concludes with a chapter on the opsonic antibodies and their function in host defense. The chapter on the white cell and platelet antigens also includes a review of the precise methodologies of DNA and HLA typing. There is also a new chapter on the immunogenetic basis for the development of certain autoimmune diseases. The chapter on the production, storage and evaluation of blood products includes a review of the definitions of the various blood components, the interactions among these components and the various synthetic hemoglobins and red cell substitutes. An important part of this chapter is the review of the various serologic tests used to measure the hematocrit and hemoglobin of RBCs. The chapter on non-erythroid red cells and white cells includes a review of the various methods used to determine blood group and typing of platelets. The chapter on the clinical uses of the various blood components concludes by providing an overview of the transfusion management for patients with cardiovascular, oncologic and hematologic disorders. This chapter also includes a listing of bloodborne viruses and non-infectious diseases. In addition, each chapter concludes with a summary of conclusions and a review of the literature. Another important aspect of this edition is the creation of a new chapter on the subject of transfusion quality improvement. This chapter is based on the extensive work of the Transfusion Medicine Quality Improvement Committee of the American Medical Association.
Thus, the LSM images have revealed the crack behaviors of the Ti film on the PDMS substrates at the micro- and nanoscales. The LSM images are found to be consistent with the optical microscopy images, as shown in Figure 2g,h. From the results obtained so far, it is found that the crack formation mainly occurs during the deformation of the PDMS substrate, and that the crack behaviors are strain dependent. The crack density is larger in the undeformed areas and becomes smaller as the strain becomes larger.
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